NSAID and Aspirin interactions have been well reported during the last decade. However, the reason behind These interaction are still unknown. This book presents the possible causes of both interacting and non- interacting NSAIDs with the cardioprotective anti-thrombotic effect of Aspirin. In the modern era of medicine, both NSAIDs and Aspirin are widely used drugs globally. The work presented in the book is a step Forward to uncover the absurd behaviour of NSAIDs with Aspirin.