The present book has been constructed to provide an overview of pattern of immune response of susceptible broiler chicks after Salmonella Gallinarum infection. The effect of experimentally induced Salmonella Gallinarum infection on total protein, albumen, globulin concentrations in serum and serum albumen-globulin ratio, antibody titer by indirect hemagglutination technique and IgG concentration by SRID techniques has also been highlighted. There is increase in concentrations of serum proteins and IgG levels and rise in antibody titer. Chickens are the natural hosts of Salmonella Gallinarum, the causative organism of fowl typhoid. Its host perimeter is limited to galiforme birds.