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The Cell Cycle in the Central Nervous System
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The Cell Cycle in the Central Nervous System

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ISBN-13:
9781597450218
Einband:
Ebook
Seiten:
584
Serie:
Contemporary Neuroscience
eBook Typ:
PDF
eBook Format:
PDF
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:

"Cell Cycle in the Central Nervous System overviews the changes in cell cycle as they relate to prenatal and post natal brain development, progression to neurological disease or tumor formation.Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle."
"Part I. Cell Cycle During the Development of the Mammalian Central Nervous System



Methodological Considerations in the Evaluation of the Cell Cycle in the Central Nervous System

Richard A. Prayson



Neural Stem Cells

Philippe Taupin



Progenitors and Precursors of Neurons and Glial Cells

Monika Bradl



Vasculogenesis and Angiogenesis

Gerald A. Grant and Damir Janigro



Neuronal Migration and Malformations of Cortical Development

Giorgio Battaglia and Stefania Bassanini



Part II. Postnatal Development of Neurons and Glia



Genome-Wide Expression Profiling of Neurogenesis in Relation to Cell Cycle Exit

P. Roy Walker, Dao Ly, Qing Y. Liu, Brandon Smith, Caroline Sodja, Marilena Ribecco, and Marianna Sikorska



Neurogenesis and Apoptotic Cell Death

Klaus van Leyen, Seong-Ryong Lee, Michael A. Moskowitz, and Eng H. Lo



Ion Channels and the Cell Cycle

Annarosa Arcangeli and Andrea Becchetti



Nonsynaptic GABAergic Communication and Postnatal Neurogenesis

Xiuxin Liu, Anna J. Bolteus, and Angélique Bordey



Critical Roles of Ca2+ and K+ Homeostasis in Apoptosis

Shan Ping Yu



Mammalian Neural Stem Cell Renewal

Yvan Arsenijevic



Part III. Control of the Cell Cycle and Apoptosis in Glia



Methods of Determining Apoptosis in Neuro-Oncology: Review of the Literature

Brian T. Ragel, Bardia Amirlak, Ganesh Rao, and William T. Couldwell



Cell Cycle, Neurological Disorders, and Reactive Gliosis

Kerri L. Hallene and Damir Janigro



Potassium Channels, Cell Cycle, and Tumorigenesis in the Central Nervous System

Gabriele Dini, Erin V. Ilkanich, and Damir Janigro



Part IV. Adult Neurogenesis: A Mechanism for Brain Repair?



Enhanced Neurogenesis Following Neurological Disease

Philippe Taupin



Endothelial Injury and Cell Cycle Re-Entry

Ljiliana Krizanac-Bengez



The Contribution of Bone Marrow-Derived Cells to Cerebrovascular Formation and Integrity

David Kobiler and John Glod



Microvessel Remodeling in Cerebral Ischemia

Danica B. Stanimirovic, Maria J. Moreno, and Arsalan S. Haqqani



Vascular and Neuronal Effects of VEGF in the Nervous System: Implications for Neurological Disorders

Lieve Moons, Peter Carmeliet, and Mieke Dewerchin



Epidermal Growth Factor Receptor in the Adult Brain

Carmen Estrada and Antonio Villalobo



Part V. Cell Cycle Re-Entry: A Mechanism of Brain Disease?



Neurodegeneration and Loss of Cell Cycle Control in Postmitotic Neurons

Randall D. York, Samantha A. Cicero, and Karl Herrup



Cell Cycle Activation and the Amyloid-b Protein in Alzheimer's Disease

Katarzyna A. Gustaw, Gemma Casadesus, Robert P. Friedland, George Perry, and Mark A. Smith



Neuronal Precursor Proliferation and Epileptic Malformations of Cortical Development

Jorge A. González-Martínez, William E. Bingaman, and Imad M. Najm



Vascular Differentiation and the Cell Cycle

Luca Cucullo



Adult Neurogenesis and Central Nervous System Cell Cycle Analysis: Novel Tools for Exploration of the Neural Causes and Correlates of Psychiatric Disorders

Amelia J. Eisch and Chitra D. Mandyam



Neurogenesis in Alzheimer's Disease: Compensation, Crisis, or Chaos?

Gemma Casadesus, Xiongwei Zhu, Hyoung-gon Lee, Michael W. Marlatt, Robert P. Friedland, Katarzyna A. Gustaw, George Perry, and Mark A. Smith



Part VI. The Biology of Gliomas



p53 and Multidrug Resistance Transporters in the Central Nervous System

Shirley Teng and Micheline Piquette-Miller



Signaling Modules in Glial Tumors and Implications for Molecular Therapy

Gurpreet S. Kapoor and Donald M. O'Rourke



Detection of Proliferation in Gliomas by Positron Emission Tomography Imaging

Alexander M. Spence, David A. Mankoff, Joanne M. Wells, Mark Muzi, John R. Grierson, Janet F. Eary, S. Finbarr O'Sullivan, Jeanne M. Link, Daniel L. Silbergeld, and Kenneth A. Krohn



Transition of Normal Astrocytes Into a Tumor Phenotype

Sean E. Aeder and Isa M. Hussaini



Mechanisms of Gliomagenesis

Wei Zhang and Howard A. Fine



Part VII. Future Directions



Cell Cycle of Encapsulated Cells

Roberto Dal Toso and Sara Bonisegna



Viral Vector Delivery to Dividing Cells

Yoshinaga Saeki



Electrical Stimulation and Angiogenesis: Electrical Signals Have Direct Effects on Endothelial Cells

Min Zhao



Development and Potential Therapeutic Aspects of Mammalian Neural Stem Cells

L. Bai, S. L. Gerson, and R. H. Miller



Mammalian Sir2 Proteins: A Role in Epilepsy and Ischemia

Barbara Aumayr and Damir Janigro



Index"
Cell Cycle in the Central Nervous System overviews the changes in cell cycle as they relate to prenatal and post natal brain development, progression to neurological disease or tumor formation.Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.