Cancer Cell Signaling

Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment.

Use of Biguanides to Improve Response to Chemotherapy.- Evaluating Response to Metformin/Cisplatin Combination in Cancer Cells Via Metabolic Measurement and Clonogenic Survival.- Quantifying the Autophagy-Triggering Effects of Drugs in Cell Spheroids with Live Fluorescence Microscopy.- Interdependency Between Genetic and Epigenetic Regulatory Defects in Cancer.- Experimental Strategies to Manipulate the Cellular Levels of the Multifunctional Factor CTCF.- Use of Serum-Circulating miRNA Profiling for the Identification of Breast Cancer Biomarkers.- Prostate Cancer Detection Using a Non-Invasive Method for Quantifying mi RNAs.- DNA Methylation Analysis of Steroid Hormone Receptor Genes.- Control of Oncogenic mi RNA Function by Light-Activated mi RNA Antagomirs.- Methods for the Study of Long Non-Coding RNA in Cancer Cell Signaling.- Microvesicles as Mediators of Intercellular Communication in Cancer.- In Vivo Rat Model to Study Horizontal Tumor Progression.- An In Vivo Model to Study the Effects of Tumoral Soluble Factors on the Vascular Permeability in Mice.- Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis.- Zebrafish-Based Systems Pharmacology of Cancer Metastasis.- A Flow Cytometry-Based Assay for the Evaluation of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in Cancer Cells.- Gene Disruption Using Zinc Finger Nuclease Technology.