AHA-BUCH

Brain Immune System Signal Molecules in Protection from Aerobic and Anaerobic Infections
-31 %
Der Artikel wird am Ende des Bestellprozesses zum Download zur Verfügung gestellt.

Brain Immune System Signal Molecules in Protection from Aerobic and Anaerobic Infections

 eBook
Sofort lieferbar | Lieferzeit:3-5 Tage I

Unser bisheriger Preis:ORGPRICE: 274,95 €

Jetzt 190,39 €*

ISBN-13:
9781461436676
Einband:
eBook
Seiten:
200
Autor:
Armen A. Galoyan
Serie:
6, Advances in Neurobiology
eBook Typ:
PDF
eBook Format:
PDF
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:

This book surveys neuroimmune function, and describes antibacterial, neuroprotective and neuroregenerative properties of proline-rich polypeptides. Reviews the action of galarmin in targeting anthrax, tuberculosis, staphylococcus and other pathogens.
The Cytokine System.- The Discovery of the Brain Immunomodulalors.- Brain Neuroendocrine Immune System: Neurosecretion of Interleukins and New Cytokines by NSO and NPV of Hypothalamus.- Antibacterial and Antiviral Activity of Galarmin (PRP-1) and Some Immunological Mechanisms of its Action.- Treatment and Prophylaxis of Anthrax by Galarmin: Receptor Tyrosine Kinase is a Target of Galarmin.- Prophylaxis and Treatment of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Infection by Galarmin and D-15 Galarmin in Vivo.- Treatment of Clostridium Perfringens-Induced Gas Gangrene by New Cytokines of Brain.- Investigation of Protective and Immunogenic Properties of Hypothalamic Proline Polypeptides Galarmin and Gx-NH2 Against Mycobacterium Tuberculosis.- Brain - Bone Marrow Neurohumoral Axis: Galarmin Controls Differentiation, Proliferation and Mobilization of Bone-Marrow Progenitor Cells.- Antioxidant-Antiradical and Electron Donating Functions of Galarmin and Gx-NH2.- Discussion.- Summary.Galarmin and Gx-NH2.- Discussion.- Summary.
Proline-rich polypeptides - in particular (PRP-1) galarmin and its structural analogues - are, when isolated from the neurosecretory granules of neurohypophysis of humans and animals, a new type of hypothalamic peptides. They work against aerobic, anaerobic, gram-positive, and gram-negative microorganisms in vivo, and do not have etiotropic properties. They are unique and capable substitutes to antibiotics, and, moreover, may be effective against strains, such as MRSA, that develop resistance to antibiotics. Galarmin, a component of the brain neuroendocrine system produced by the neurosecretory cells of hypothalamus, possesses  immunomodulative, neuroprotective, antioxidant, antitumorigenic and hematopoietic properties. Moreover, galarmin and its structural analogues are powerful anti-inflammatory  compounds.