Brain Immune System Signal Molecules in Protection from Aerobic and An

Dr. Galoyan is a pioneer of the specialized field of neuroimmunology. During his 45-year-long career, he has discovered a neuroendocrine immune system of the brain and identified a new type of brain cytokines: proline-rich polypeptides. The most important of these, PRP-1 (galarmin) has been shown to possess antibacterial properties and protect from certain neurotoxins.

This book surveys neuroimmune function, and describes antibacterial, neuroprotective and neuroregenerative properties of proline-rich polypeptides. Reviews the action of galarmin in targeting anthrax, tuberculosis, staphylococcus and other pathogens.

The Cytokine System.- The Discovery of the Brain Immunomodulalors.- Brain Neuroendocrine Immune System: Neurosecretion of Interleukins and New Cytokines by NSO and NPV of Hypothalamus.- Antibacterial and Antiviral Activity of Galarmin (PRP-1) and Some Immunological Mechanisms of its Action.- Treatment and Prophylaxis of Anthrax by Galarmin: Receptor Tyrosine Kinase is a Target of Galarmin.- Prophylaxis and Treatment of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Infection by Galarmin and D-15 Galarmin in Vivo.- Treatment of Clostridium Perfringens-Induced Gas Gangrene by New Cytokines of Brain.- Investigation of Protective and Immunogenic Properties of Hypothalamic Proline Polypeptides Galarmin and Gx-NH2 Against Mycobacterium Tuberculosis.- Brain - Bone Marrow Neurohumoral Axis: Galarmin Controls Differentiation, Proliferation and Mobilization of Bone-Marrow Progenitor Cells.- Antioxidant-Antiradical and Electron Donating Functions of Galarmin and Gx-NH2.- Discussion.- Summary.Galarmin and Gx-NH2.- Discussion.- Summary.