Preface - Introduction - Principles - Questions - Ideas - Principles of Truth and Acceptance - Presumption as a Pathway to Plausibility - Conjecture and the Move from Mere Plausibility and Presumption to Acceptance - Plausibility Conflicts and Paradox - From Conjecture to Belief and from Belief to Knowledge - The Epistemic Gap and Grades of Acceptance - Cognitive Thresholds - Imprecision - Intuitive Knowledge - Experience and Induction - Distributive vs. Collective Explanation - Cognitive Importance - Problems of Prediction - Error and Cognitive Risk - Problems of Skepticism - Trust - Common Sense - How Science Works - Scientific Realism and Its Problems - The Anthomorphic Contextuality of Science - Ignorance and Limits of Knowledge - On Systemic "Best Fit" Reasoning - Inference from the Best Systematization - The Cyclic Unity of Reason - Fact, Fiction, and Functional Surrogacy - A Pragmatic Coda - Bibliography - Name Index.