Multiple Sclerosis and CNS Inflammatory Disorders

Multiple Sclerosis and CNS Inflammatory Disorders is apractical guide to effective care of patients with multiplesclerosis and other neuroimmunologic and CNS inflammatorydisorders.It provides the scientific basis of multiple sclerosis includingetiology, epidemiology, and pathogenesis. It covers the diagnosticprocess, the course of the disease and prognosis, and the use ofMRI in diagnosis and disease monitoring. Disease-modifyingtreatment algorithms for relapsing-remitting multiple sclerosis,switching therapy, and progressive multiple sclerosis treatmentalgorithms are all discussed in detail. It also addresses multiplesclerosis in childhood and pregnancy and includes assessment ofalternative therapies.This new addition to the Neurology in Practice series containspractical guidance and learning features:* Algorithms and guidelines* "Tips and Tricks" boxes on improvingoutcomes* "Caution" warning boxes to avoidingproblems* "Science Revisited"--quick reminders ofthe basic science principles necessary for understandingMultiple Sclerosis and CNS Inflammatory Disorders is anideal reference for neurologists in practice and training.

Contributors viiSeries Foreword xPreface xichapter 1 1EtiologySonya U. Steele and Ellen M. Mowrychapter 2 10Immunopathogenesis of Multiple SclerosisAnne H. Cross and Laura Picciochapter 3 18Diagnostic ProcessDalia Rotstein and Paul O'Connorchapter 4 29MRI in Diagnosis and Disease MonitoringMaría I. Gaitán and Daniel S. Reichchapter 5 45Relapsing MS: Disease Staging and Therapeutic AlgorithmsMohsen Khoshnam and Mark Freedmanchapter 6 57Progressive MS Treatment AlgorithmsMegan H. Hyland and Jeffrey A. Cohenchapter 7 67Sex-Determined Issues in Multiple SclerosisCallene Momtazee and Barbara Giesserchapter 8 77Pediatric Multiple SclerosisRobert Thompson Stone and Brenda Banwellchapter 9 91Complementary and Alternative Medicine: Risks and BenefitsAllen C. Bowlingchapter 10 102Symptomatic Management of MSJessica Robb, Lawrence M. Samkoff, and Andrew D. Goodmanchapter 11 114Invisible Symptoms of MS: Fatigue, Depression, andCognitionLeigh E. Charvet, Benzi Kluzer, and Lauren B. Kruppchapter 12 122RehabilitationNesanet S. Mitiku, Alexius E. G. Sandoval, and George H.Kraftchapter 13 134Psychosocial Adaptation to Multiple SclerosisDavid J. Rintellchapter 14 144Transverse Myelitis and Acute DisseminatedEncephalomyelitisBenjamin M. Greenbergchapter 15 153Neuromyelitis OpticaMarcelo Matiello and Brian G. Weinshenkerchapter 16 163NeurosarcoidosisThomas F. Scottchapter 17 169Lyme NeuroborreliosisErica Patrick and Eric Logigianchapter 18 178Neuro-Behçet SyndromeAksel Siva and Sabahattin SaipIndex 191