Fluid Dynamics as a Localizing Factor for Atherosclerosis

InhaltsangabeOpening Comments.- Fluid Dynamic Approaches to Atherosclerosis.- A Fluid-Dynamicist's and a Physiologist's Look at Arterial Flow and Arteriosclerosis.- The Case for Fluid Dynamics as a Localizing Factor in Atherogenesis.- Flow and Atherogenesis in the Human Carotid Bifurcation.- Pulsating Flow in Distensible Models of Vascular Branches.- Coronary Artery Geometry and Its Fluid Mechanical Implications.- Flow Patterns in Model and Natural Branching Vessels.- Geometric Effects on the Hemodynamic Environment of the Arterial Wall: A Basis for Geometric Risk Factors?.- The Drainage of Transmural Flow and the Consequences of Its Insufficiency.- Fluid Mechanical Factors in Macromolecular Transport by the Arterial Wall.- The Role of Hydrodynamic Factors in Platelet Activation and Thrombotic Events: The Effects of Shear Stress of Short Duration.- Microrheology of Thrombocyte Deposition: Effect of Stimulation, Flow Direction, and Red Cells.- The Localization of Transient Subendothelial Water-Filled Blisters in the in Situ Rabbit Aorta as a Result of Reduction in Pressure.- Influence of Convection and Vasoactive Agents on the Mass Transport Properties of the Arterial Wall.- Haemodynamic Influences on Platelets in Haemostasis and Thrombosis.- Effects of Antihypertensive Drugs and Blood Velocity.- General Properties of Endothelial Cells.- The Endothelium as a Mediating Factor in Transport Across the Arterial Wall.- Morphology and Fluid-Dynamics of Endothelial Cells at the Site of Vascular Bifurcation.- Location and Morphology of Hypertensive Lesions in Coronary Arteries of Dogs.- Response of Vascular Endothelium to Unsteady Fluid Shear Stress in Vitro.- Injury at the Vascular Surface.- Cellular Participation in Atherogenesis: Selected Facets of Endothelium, Smooth Muscle, and the Peripheral Blood Monocyte.- Evidence that High Flow Velocity and Endothelial Disruption Are Not the Principal Factors in Experimental Plaque Localization.- Localization of Early Atherosclerotic Lesions in Carotid and Coronary Bifurcations in Humans - A Bifurcation of the High Shear Stress Hypothesis.- Quantitative Arterial Wall Morphology.

Opening Comments.- Fluid Dynamic Approaches to Atherosclerosis.- A Fluid-Dynamicist's and a Physiologist's Look at Arterial Flow and Arteriosclerosis.- The Case for Fluid Dynamics as a Localizing Factor in Atherogenesis.- Flow and Atherogenesis in the Human Carotid Bifurcation.- Pulsating Flow in Distensible Models of Vascular Branches.- Coronary Artery Geometry and Its Fluid Mechanical Implications.- Flow Patterns in Model and Natural Branching Vessels.- Geometric Effects on the Hemodynamic Environment of the Arterial Wall: A Basis for Geometric Risk Factors?.- The Drainage of Transmural Flow and the Consequences of Its Insufficiency.- Fluid Mechanical Factors in Macromolecular Transport by the Arterial Wall.- The Role of Hydrodynamic Factors in Platelet Activation and Thrombotic Events: The Effects of Shear Stress of Short Duration.- Microrheology of Thrombocyte Deposition: Effect of Stimulation, Flow Direction, and Red Cells.- The Localization of Transient Subendothelial Water-Filled Blisters in the in Situ Rabbit Aorta as a Result of Reduction in Pressure.- Influence of Convection and Vasoactive Agents on the Mass Transport Properties of the Arterial Wall.- Haemodynamic Influences on Platelets in Haemostasis and Thrombosis.- Effects of Antihypertensive Drugs and Blood Velocity.- General Properties of Endothelial Cells.- The Endothelium as a Mediating Factor in Transport Across the Arterial Wall.- Morphology and Fluid-Dynamics of Endothelial Cells at the Site of Vascular Bifurcation.- Location and Morphology of Hypertensive Lesions in Coronary Arteries of Dogs.- Response of Vascular Endothelium to Unsteady Fluid Shear Stress in Vitro.- Injury at the Vascular Surface.- Cellular Participation in Atherogenesis: Selected Facets of Endothelium, Smooth Muscle, and thePeripheral Blood Monocyte.- Evidence that High Flow Velocity and Endothelial Disruption Are Not the Principal Factors in Experimental Plaque Localization.- Localization of Early Atherosclerotic Lesions in Carotid and Coronary Bifurcations in Humans - A Bifurcation of the High Shear Stress Hypothesis.- Quantitative Arterial Wall Morphology.