Transluminal Coronary Angioplasty and Intracoronary Thrombolysis

This volume contains the proceedings of the Fourth International Symposium on Coronary Heart Disease, held in Frankfurt/Federal Republic of Germany. In 1970, when the fIrst symposium was held, the whole range of diagnostic and therapeutic measures was covered, but since then interest in coronary heart disease has increased so considerably that the fourth symposium was restricted to only two therapeutic aspects, angioplasty and intracoronary thrombolysis. It can be noted with pleasure that European cardiologists, namely Andreas Griintzig and Peter Rentrop, have made essential contributions to the applicability of these modes of treatment. When angioplasty was fIrst discussed at the Third International Symposium (Coronary Heart Disease, Stuttgart, 1978) a great deal of astonishment was expressed. Today the procedure has gained an important place in the treatment of angina pecto ris. The proportion of candidates for coronary surgery in whom angioplasty can be attempted instead of operation is around 10%, in certain subgroups even higher. The most remarkable fmding of our 5-year experience with angioplasty are the extre mely good long-term results. Recurrences happen in about 15%-20% of cases within the fIrst 3 months; after this period of time, recurrences are very unusual and mostly due to progression of the disease at other sites. Angioplasty has thus also contributed to our understanding of the dynamics of the atherosclerotic process.

With contributions by numerous experts

Transluminal Angioplasty. Development and Experiences.- Percutaneous Transluminal Angioplasty.- Transluminal Coronary Angioplasty: Results, Complications, Follow-up, and Consideration of Extension of Indications. An Analysis of 409 Procedures.- The National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry: The First 1116 Cases.- Immediate and Late Results of Percutaneous Transluminal Coronary Angioplasty.- Transluminal Coronary Angioplasty: Transbrachial Approach and Prevention of Thromboembolic Complications.- Treatment with Platelet Function Inhibitors.- Functional Results of TCA.- Effects of Percutaneous Transluminal Coronary Angioplasty on Myocardial Function During Exercise.- Myocardial Function Before and After Transluminal Coronary Angioplasty.- Interest of Radionuclide Methods for the Assessment of the Results of Percutaneous Transluminal Coronary Angioplasty.- Parameters of Left Ventricular Contractility After Transluminal Coronary Angioplasty.- Dynamic Changes in Left Ventricular Geometry and Pressure During Coronary Artery Occlusion in Man.- Salutory Effect of Percutaneous Transluminal Coronary Angioplasty on Coronary Circulatory Dynamics.- Overview.- Successful and Unsuccessful TCA.- Unsuccessful Percutaneous Transluminal Coronary Angioplasty: Identification of Remedial Causes.- Criteria for Primary Success and Long-term Results. Analysis of 152 Consecutive Transluminal Coronary Angioplasties.- Changes of Coronary Obstructions in the Months Following Transluminal Coronary Angioplasty.- Computerized Quantitative Coronary Angiography Applied to Percutaneous Transluminal Coronary Angioplasty: Advantages and Limitations.- Techniques.- Cinefluoroscopic and Video Imaging in Percutaneous Transluminal Coronary Angioplasty.- Biplane Isocentric Coronary Angiography in Diagnosis and Interventional Therapy.- Percutaneous Transluminal Coronary Angioplasty: Comparison of Brachial and Femoral Artery Methods.- Complications.- The Role of the Percutaneous Intra-aortic Balloon in Emergency Situations Following Percutaneous Transluminal Coronary Angioplasty.- Emergency Reopening of Right Coronary Occlusion After Angioplasty Using Guide Wire and Thrombolysis.- Experimental Results.- Morphology and Pathogenesis of Coronary Artery Stenosis, Relevant to Intraluminal Dilatation.- Morphology and Pathogenesis of the Aortocoronary Bypass Stenosis.- A New Guiding Catheter for Intubating Aortocoronary Bypass Grafts by the Femoral Approach.- Histological Changes Following Transluminal Angioplasty of Experimentally Induced Atherosclerosis in Miniature Pigs.- Correlation of the Effects of Transluminal Angioplasty in Experimentally Induced Rabbit Atherosclerosis with Pathological Changes in Human Coronary Artery.- Acute and Chronic Effects of Transluminal Angioplasty in Three Models of Experimental Atherosclerosis.- Effects of 5 kg/cm2 Pressure on Atherosclerotic Vessel Wall Segments.- Overview.- New Applications of Transluminal Angioplasty.- Coronary Angiography in Combination with Opacification of Other Arteries and Simultaneous Transbrachial Dilatation of Peripheral and Abdominal Arteries.- Transluminal Angioplasty for Vertebral Basilar Artery Stenosis.- Catheter Dilatation in Subclavian Steal Syndrome.- Overview.- Coronary Fibrinolysis in Acute Myocardial Infarction.- Percutaneous Transluminal Coronary Recanalization: Procedures, Results, and Acute Complications.- Rapid Intracoronary Thrombolysis by Subselective Administration of Thrombolytic Agents.- The Morphology of Coronary Thrombotic Occlusions Relevant to Thrombolytic Intervention.- Fibrinogen in Successful and Unsuccessful Cases.- Preservation of Function by Nonsurgical Coronary Artery Reperfusion.- Left Ventricular Function After Reopening of Occluded Coronary Arteries.- Collaterals May Determine the Functional Result of Intracoronary Streptokinase Therapy After Acute Myocardial Infarction.- Intracoronary Fibrinolysis in Acute Myocardial Infarction. Effect on Left Ventricular Function.- Two-dimensional Echocardiographic Findings in Patients with Evolving Myocardial Infarction Treated by Intracoronary Fibrinolysis.- Intracoronary Fibrinolysis in Acute Myocardial Infarction: Hospital Follow-up.- Relevance of Hemorrhage After Reperfusion in Acute Myocardial Infarction.- A New Concept in Producing Experimental Myocardial Infarction: Intracoronary Applications of Thrombin.- Thrombolysis in Acute Experimental Myocardial Infarction.- Serum Creatine Kinase Values in the Course of Acute Myocardial Infarction Following Local Fibrinolytic Therapy.- Effects of Coronary Artery Reperfusion on Myocardial Infarct Size in Conscious Dogs.- Coronary Artery Recanalization and Subsequent Aortocoronary Bypass Surgery in Acute Myocardial Infarction.- Combined Intracoronary Fibrinolysis and Early Aortocoronary Bypass Graft.- Surgical Revascularization After Intracoronary Lysis.- Systemic Short-Time Thrombolysis in Acute Myocardial Infarction.- The Use of Plasminogen in Intracoronary Lysis.- Overview.- Borderline Indications for TCA.- Preliminary Experience with Percutaneous Transluminal Coronary Angioplasty in Patients with Coronary Spasm.- Transluminal Coronary Angioplasty and Coronary Spasm.- Morphological and Functional Criteria for a Successful Percutaneous Transluminal Angioplasty.- Transluminal Angioplasty in Patients with Unstable Angina Pectoris.- Adrenergic Coronary Vasoconstriction with Coronary Stenosis.- Variant Angina: The Role of Thromboxane A2 with Observations on the Importance of Study Design.- Prostaglandin Derivatives and Platelet-specific Proteins During Transluminal Coronary Angioplasty.- Persistent Angina After Transmural Infarction due to High-grade Single-vessel Stenosis.- Prognosis of Nontransmural Myocardial Infarction.- Overview.- Angioplasty in Peripheral and Renal Arteries.- Percutaneous Transluminal Recanalization (Angioplasty) in Leg Arteries.- The Fate of "No Angioplasty" in Peripheral Vascular Disease.- Percutaneous Transluminal Renal Angioplasty: Experience in Over 100 Arteries.- Percutaneous Transluminal Dilatation (Angioplasty) in Renal Arteries.- Percutaneous Transluminal Angioplasty in the Treatment of Renovascular Hypertension.- Overview.

With contributions by numerous experts