QSAR of pyrrolo benzodiazepine derivatives
Pyrrolo benzodiazepine as anti cancer agents
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Lieferzeit: Print on Demand - Lieferbar innerhalb von 3-5 Werktagen I
ISBN-13:
9783639377842
Einband:
.
Seiten:
56
Autor:
Sumitra Nain
Format:
22.00x15.00x0.30 cm
Sprache:
Englisch
Beschreibung:
Quantitative structure activity relationship studies are indubitably of great importance in modern chemistry. In pursuit of better anti-cancer agents QSAR studies were performed on a series of pyrrolo-benzodiazepine derivatives. The models were developed using training set compounds employing multiple linear regression and partial least square with many descriptors like electronic, topological, and geometrical. The developed models were evaluated for statistical significance and predictive power