Comparison of Suspected Adverse Drug Reactions to Some Antimalarial

From the year 2000, many different types of antimalarial medications were distributed in sub-Saharan Africa for the treatment of malaria in children, pregnant women and the general public. Based on the Abuja Declaration and Plan of Action agreed upon in April 25, 2000, Artemisinin-based Combination Therapy (ACTs) antimalarial such as Artemether-Lumefantrin and Artesunate Amodiaquine were purchased and used among malaria-infected patients. However, there was little attention paid to the Adverse Drug Reactions (ADRs) of these malaria medications among the general public. Some of the ADRs that were reported included mild, moderate or severe headache, weakness, fatigue, itching, abdominal pain, body swelling, dizziness and others, depending on which anti-malaria medication was consumed. The severity of these ADRs may be depended on whether the patient took the medication with or without fatty meal as indicated in instruction for users. This book is the product of a study on ADRs among adults in a semi-urban area of Lagos Nigeria. The book suggests that renal impairment, which became rampant in Nigeria, may be due to consumption of some or all of these antimalarial.