Biomaterials, Artificial Organs and Tissue Engineering

Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues.

Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues.Comprehensive introduction to living and man-made materialsLooks at clinical applications of various biomaterials and devicesBioengineering principles, materials and designs used in artificial organs are summarised

Part 1 Introduction to materials (living and non-living): Metals; Ceramics; Polymers; Biocomposites; Cells and tissues; Inflammation and wound healing. Part 2 Clinical needs and concepts of repair: The skeletal system; The cardiovascular system; Biomedical polymers; Biomedical hydrogels. Part 3 Applications: Repair of skeletal tissues; Joint replacement; Artificial organs; Mass transport processes in artificial organs; Artificial exchange systems; Cardiovascular assist systems. Part 4 Tissue engineering: Introduction to tissue engineering; Scaffolds for tissue engineering; A guide to basic cell culture and applications in biomaterials and tissue engineering; Immunochemical techniques in tissue engineering and biomaterial science; Clinical applications of tissue engineering. Part 5 Societal, regulatory and ethical issues: Regulatory classification of biomaterials and medical devices; Technology transfer; Ethical issues.