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Comparative Pharmacokinetics
160,99 €*
ISBN-13:
9780470959886
Veröffentl:
2011
Einband:
E-Book
Seiten:
376
Autor:
Jim E. Riviere
eBook Typ:
EPUB
eBook Format:
Reflowable
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.
Coauthors.Preface.1 Introduction.2 Principles of Drug Movement in the Body.3 Quantitative Structure-Permeability Relationships(Xin-Rui Xia).4 Absorption.5 Distribution (with Jennifer Buur).6 Renal Elimination.7 Hepatic Biotransformation and Biliary Excretion (RonaldBaynes).8 Compartmental Models.9 Noncompartmental Models.10 Nonlinear Models.11 Physiological Models (Teresa Leavens).12 Dosage Regimens.13 Simultaneous Pharmacokinetic-Pharmacodynamic Modeling(Pierre-Louis Toutain).14 Study Design and Data Analysis. (JasonChittenden).15 Bioequivalence Studies (Marilyn Martinez).16 Population Pharmacokinetic Models (JasonChittenden).17 Dosage Adjustments in Disease States (JenniferDavis).18 Interspecies Extrapolations.19 Tissue Residues and Withdrawal Times (SharonMason).Index.